Aspirin, one of the world's most famous and widely used medications, was first registered on March 6, 1899, by the German company Bayer AG. The active ingredient, acetylsalicylic acid, was synthesized by chemist Felix Hoffmann. His motivation was personal; he sought a less irritating substitute for salicylic acid to alleviate his father's rheumatism. The history of aspirin's active ingredient dates back centuries, with salicylate-rich willow bark being used for pain relief and fever reduction in various cultures. However, it was not until the 19th century that scientists began to isolate and modify salicylic acid to reduce its side effects, leading to the creation of acetylsalicylic acid. Upon its release, aspirin quickly became a staple in medicine cabinets worldwide, renowned for its efficacy in reducing pain, fever, and inflammation. Over time, studies also revealed aspirin's role in reducing the risk of heart attacks and strokes, attributing to its blood-thinning properties. Internationally, aspirin is known by various names, such as "acetylsalicylic acid" in scientific communities and "aspirina" in several Latin languages. In some countries, it is sold under different brand names, but "aspirin" remains a globally recognized term. Aspirin's name comes from "A" for acetyl, "spir" from the spirea plant (a source of salicylate), and "in," a common suffix for medications at the time. More: https://en.wikipedia.org/wiki/Aspirin Art&Text supported by ChatGPT.