Felix Hoffmann, a chemist at the German pharmaceutical company Bayer, synthesized acetylsalicylic acid in a pure and stable form in 1897. Bayer patented the drug on March 6, 1899 under the name "Aspirin," issued in the US as patent 644,077, on 27 February 1900. It quickly became the world's most widely used medication (and it is today as of 2017). Aspirin was touted for its pain-relieving, anti-inflammatory, and antipyretic (fever-reducing) properties. It was indicated for a variety of conditions, including headache, dental pain, menstrual cramps, muscle and joint aches, and fever. Aspirin started as powder, but soon enough was pressed into tablets with the iconic Bayer logo. In the 1970s, studies began to reveal its potential in preventing heart attacks, leading to its use in low doses for cardiovascular protection. In 1982, Sir John Vane won a Nobel Prize for discovering aspirin's action in inhibiting prostaglandin synthesis. Today, Aspirin is on the World Health Organization's List of Essential Medicines, highlighting its importance in global health. It's estimated that annually, over 60 billion Aspirin tablets (35,000+ tons) are consumed worldwide, and a trillion since 100 years, underscoring its enduring impact on medicine. Its adoption for cardiovascular disease prevention and its role in pain and fever management make it a cornerstone of modern therapy. More: https://en.wikipedia.org/wiki/History_of_aspirin Art&Text🫶ChatGPT.